When Yale psychiatrist, John Krystal, discovered the antidepressant effects of ketamine in the late 1990s, he set off a domino effect that would ultimately change the way scientists and medical researchers understand depression and how it works in the brain. Up until...

Many people think of ketamine as a “club drug.” Ketamine, however, has a long history of medical use, with mounds of research to support its safety and efficacy when administered by trained professionals. Most commonly, ketamine is used as an anesthetic for surgery in...